Catalytic residues in hydrolases: analysis of methods designed for ligand-binding site prediction
نویسندگان
چکیده
منابع مشابه
Catalytic residues in hydrolases: analysis of methods designed for ligand-binding site prediction
The comparison of eight tools applicable to ligand-binding site prediction is presented. The methods examined cover three types of approaches: the geometrical (CASTp, PASS, Pocket-Finder), the physicochemical (Q-SiteFinder, FOD) and the knowledge-based (ConSurf, SuMo, WebFEATURE). The accuracy of predictions was measured in reference to the catalytic residues documented in the Catalytic Site At...
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ژورنال
عنوان ژورنال: Journal of Computer-Aided Molecular Design
سال: 2010
ISSN: 0920-654X,1573-4951
DOI: 10.1007/s10822-010-9402-0